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How does mesalazine work in the body?
Mesalazine works by reducing the inflammation in the intestine, which in turn reduces the symptoms of the disease. The way in which mesalazine does this is not fully understood. Pentasa suppositories are administered into the back passage (rectum) to treat disease affecting the rectum (ulcerative proctitis).
What is the difference between mesalazine and mesalamine?
Mesalamine is absorbed in the upper gastrointestinal tract; 3 – 5 whereas, it exerts antiinflammatory activity directly on the inflamed mucosa in colon and rectum. Thus, many types of release-controlled oral formulations of mesalamine have been developed to enhance its effect.
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